Surgical treatment of pulmonary arteriovenous malformation: Report of two cases and review of the literature

METİN S. K., Karacelik M., Yavaccan O., Celik M., Cetin N., Dorak M., ...More

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol.33, no.4, pp.467-471, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 4
  • Publication Date: 2005
  • Doi Number: 10.1177/147323000503300413
  • Journal Name: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.467-471
  • Keywords: pulmonary arteriovenous malformation, hereditary haemorrrhagic telangiectasia, cyanosis, HEREDITARY HEMORRHAGIC TELANGIECTASIA, FISTULAS
  • Dokuz Eylül University Affiliated: No

Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare anomalies. The degree of right-to-left shunting, which can lead to cyanosis and paradoxical embolism causing neurological complications, determines the prognosis. We report two cases of PAVM and review the literature. A 45-year-old woman with clinical signs and symptoms of PAVM was examined using several different scanning techniques, which showed a large PAVM in the lower lobe of her right lung. A lobectomy was performed, which revealed a 5 cm diameter PAVM with one feeding artery and multiple veins. Intravenous angiography of a 7-year-old girl with symptoms of fatigue and acro-cyanosis confirmed the presence of a large PAVM in her right lower lobe. The PAVM had two major arteries arising from the aorta, which were ligated during a lobectomy. Both patients recovered well following surgery. Although PAVMs are rare, their neurological and haemodynamic consequences may be fatal. Interventional treatment techniques, including surgery, are usually curative.