Surgical treatment of pulmonary arteriovenous malformation: Report of two cases and review of the literature
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol.33, no.4, pp.467-471, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 33 Issue: 4
- Publication Date: 2005
- Doi Number: 10.1177/147323000503300413
- Journal Name: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.467-471
- Keywords: pulmonary arteriovenous malformation, hereditary haemorrrhagic telangiectasia, cyanosis
- Dokuz Eylül University Affiliated: No
Abstract
Pulmonary arteriovenous malformations (PAVMs) are rare anomalies. The degree of right-to-left shunting, which can lead to cyanosis and paradoxical embolism causing neurological complications, determines the prognosis. We report two cases of PAVM and review the literature. A 45-year-old woman with clinical signs and symptoms of PAVM was examined using several different scanning techniques, which showed a large PAVM in the lower lobe of her right lung. A lobectomy was performed, which revealed a 5 cm diameter PAVM with one feeding artery and multiple veins. Intravenous angiography of a 7-year-old girl with symptoms of fatigue and acro-cyanosis confirmed the presence of a large PAVM in her right lower lobe. The PAVM had two major arteries arising from the aorta, which were ligated during a lobectomy. Both patients recovered well following surgery. Although PAVMs are rare, their neurological and haemodynamic consequences may be fatal. Interventional treatment techniques, including surgery, are usually curative.