Methylation Profiling of Specific Genes in Ependymomas

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Kanit N., Yalcin P., Erbayraktar S., ÖZER E.

TURKISH JOURNAL OF PATHOLOGY, cilt.38, sa.3, ss.213-218, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5146/tjpath.2021.01565
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.213-218
  • Anahtar Kelimeler: DNA methylation, Ependymoma, Epigenetics, Pyrosequencing, MGMT PROMOTER METHYLATION, TUMORS, KRUPPEL-LIKE-FACTOR-4, CDKN2A, CLASSIFICATION, IDENTIFICATION, TRANSCRIPTION, INACTIVATION, EXPRESSION, PROGNOSIS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Ependymomas are neuroepithelial tumors of the central nervous system with heterogeneous biology and clinical course. The aim of the present study is to investigate the relationship between the methylation status and clinicopathological parameters in ependymomas.