Methylation Profiling of Specific Genes in Ependymomas


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Kanit N., Yalcin P., Erbayraktar S., ÖZER E.

TURKISH JOURNAL OF PATHOLOGY, vol.38, no.3, pp.213-218, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.5146/tjpath.2021.01565
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.213-218
  • Keywords: DNA methylation, Ependymoma, Epigenetics, Pyrosequencing, MGMT PROMOTER METHYLATION, TUMORS, KRUPPEL-LIKE-FACTOR-4, CDKN2A, CLASSIFICATION, IDENTIFICATION, TRANSCRIPTION, INACTIVATION, EXPRESSION, PROGNOSIS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Ependymomas are neuroepithelial tumors of the central nervous system with heterogeneous biology and clinical course. The aim of the present study is to investigate the relationship between the methylation status and clinicopathological parameters in ependymomas.