Relationship between BODE index, quality of life and inflammatory cytokines in COPD patients.

Sarioglu N., Alpaydin A., Coskun A. S., Celik P., Ozyurt B. C., Yorgancioglu A.

Multidisciplinary respiratory medicine, vol.5, no.2, pp.84-91, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1186/2049-6958-5-2-84
  • Journal Name: Multidisciplinary respiratory medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.84-91
  • Keywords: Biomarkers, BODE index, COPD, quality of life, OBSTRUCTIVE PULMONARY-DISEASE, C-REACTIVE PROTEIN, HEALTH-STATUS, WEIGHT-LOSS, DYSPNEA, VARIABLES, CAPACITY, ASTHMA, MASS
  • Dokuz Eylül University Affiliated: No

Abstract

Background and aims: Recently a multidimensional grading system based on the body mass index (B), degree of airflow obstruction (O), dyspnea (D) and exercise capacity (E) - the BODE index - has begun to be used increasingly for the evaluation of chronic obstructive pulmonary disease (COPD) patients. The aim of our study was to investigate the relationship between the BODE index and disease duration, annual exacerbation and hospitalization rates, health related quality of life and systemic inflammatory markers like C-reactive protein (CRP), tumor necrosis factor (TNF)-alpha and interleukin (IL)-8.