Do antiepileptic drugs cause premature atherosclerosis by disturbing lipid metabolism?

Eskut N., Soysuren C., Dogan G. M., Tuna G., Toksoz F., Calis N., ...More

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.13, no.1, pp.98-103, 2022 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.4328/acam.20820
  • Journal Name: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.98-103
  • Keywords: Epilepsy, Antiepileptic Drug, Atherosclerosis, Lipoprotein, Carotid Intima-Media Thickness, INTIMA-MEDIA THICKNESS, VASCULAR RISK-FACTORS, EPILEPTIC CHILDREN, SERUM-LIPIDS, SODIUM VALPROATE, LIPOPROTEIN, CARBAMAZEPINE, THERAPY, STROKE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Aim: The aim of this study was to evaluate susceptibility to atherosclerosis in epileptic patients on carbamazepine and valproic add monotherapy with lipid profile, lipoprotein (a) (Ip(a)), oxidized low-density lipoprotein (LDL), adiponectin, and carotid artery intima-media thickness measurements.