Disseminated Panton-Valentine Leukocidin-Positive <i>Staphylococcus</i> <i>aureus</i> infection in a child
ARCHIVOS ARGENTINOS DE PEDIATRIA, vol.114, no.2, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 114 Issue: 2
- Publication Date: 2016
- Doi Number: 10.5546/aap.2016.eng.e75
- Journal Name: ARCHIVOS ARGENTINOS DE PEDIATRIA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: Staphylococcus aureus, Panton-Valentine leukocidin, necrotizing pneumonia, sepsis
- Dokuz Eylül University Affiliated: No
Abstract
Panton-Valentine leukocidin (PVL) is an exotoxin that is produced by many strains of Staphylococcus aureus, and an important virulence factor. A PVL-positive S. aureus infection leads to rapid and severe infections of soft tissue and necrotizing pneumonia in healthy adolescents, and has a high mortality. This case report included a 12-year-old male patient who admitted for fever, respiratory distress and hip pain and was identified with necrotizing pneumonia with septic pulmonary embolism, psoas abscess, cellulitis and osteomyelitis. The PVL positive methicillin-sensitive S. aureus (MSSA) was isolated in the patient blood culture.