Equilibrium, kinetics and thermodynamic aspects of Promethazine hydrochloride sorption by iron rich smectite

SEKİ Y., YURDAKOÇ M. K.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, vol.340, pp.143-148, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 340
  • Publication Date: 2009
  • Doi Number: 10.1016/j.colsurfa.2009.03.020
  • Journal Name: COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.143-148
  • Keywords: Drug, Smectite, Adsorption, Promethazine hydrochloride, Kinetics, 6 CARBONACEOUS MATERIALS, AQUEOUS-SOLUTION, ADSORPTION EQUILIBRIUM, PROMAZINE ABSORPTION, DRUG ABSORPTION, SINGLE MODEL, REMOVAL, MONTMORILLONITE, DYE, PREDNISOLONE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Equilibrium, kinetics and thermodynamic aspects of sorption of Promethazine hydrochloride (PHCl) onto iron rich smectite (IRS) from aqueous Solution were investigated. The effect of pH on sorption of PHCl onto IRS was also found out. Experimental data were evaluated by using Langmuir, Freundlich and Dubinin-Raduschkevich (DR) isotherm equations. Freundlich and DR equations provided better compatibility than Langmuir equation. Besides, it was determined that the maximum sorption of PHCl takes place at about pH 5. From kinetic studies, it was obtained that sorption kinetics follow pseudo-second-order kinetic model for PHCl sorption onto IRS. When thermodynamic studies are concerned, the values of activation energy (E-a), Delta G, Delta H and Delta S were obtained. Delta G values are in the range of -8.84 and -9.45 kJ mol(-1) indicating spontaneous nature of physisorption. The negative value of the Delta H (-3.20 kJ mol(-1)) indicates exothermic nature of adsorption. FTIR analysis and SEM observations of IRS and PHCl adsorbed IRS were also carried Out. Sorption experiments indicate that IRS may be Used effectively for the adsorption of PHCl. (C) 2009 Elsevier B.V. All rights reserved.