Comparison of the Effects of Epicardial and Endocardial Cardiac Resynchronization Therapy on Transmural Dispersion of Repolarization

ÖZCAN E. E., Szilagyi S., Sallo Z., Molnar L., Zima E., Szeplaki G., ...More

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, vol.38, no.9, pp.1099-1105, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1111/pace.12678
  • Journal Name: PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1099-1105
  • Keywords: cardiac resynchronization therapy, transmural dispersion of repolarization, transseptal endocardial biventricular pacing, heart failure, ventricular arrhythmias
  • Dokuz Eylül University Affiliated: Yes

Abstract

BackgroundDespite significant improvements in cardiac output and functional capacity with cardiac resynchronization therapy (CRT), incidence of sudden cardiac death still remains high. Reversal of physiological myocardial activation sequence during epicardial pacing increases the transmural dispersion of repolarization (TDR). The aim of this study was to compare the effects of endocardial and epicardial biventricular pacing on repolarization parameters in the same patient group.