Objective: QOL is a multidimensional concept set as indicator to assess the effect of interventions applied to the Alzheimer patients. The objective of this study is to assess the validity and reliability of the Quality of Life in Alzheimer's Disease (QOL-AD) scale for the Turkish society. Methods: This research is a methodological study. The sample was composed of 72 individuals diagnosed with Alzheimer's disease and their caregivers. Research data were collected in the dementia outpatient clinic of a university hospital and İzmir branch of the Alzheimer's Association. QOL-AD gives information about the QOL of the patient. The scale is composed of 13 items, each of which is assessed over a 4-point scale (1 point is bad, 4 point is excellent). The minimum score obtained from the scale is 13, maximum score is 52. Results: Translation and back translation were performed to evaluate the language validity of the scale. Besides, it was determined that the expert opinions regarding the content validity were compatible (Kendall's W=.223, p=.095). Internal consistency reliability coefficient (cronbach alpha) of QOL-AD scale for the patients was found as 0.84 while intraclass correlation coefficient was found as 0.79. However, internal consistency reliability coefficient (cronbach alpha) of caregivers' reports on patients' quality of life (C-PQOL) was 0.77 while intraclass correlation coefficient was 0.72. Conclusion: The results indicate reliability and validity of the Turkish version of the QOLAD in the Turkish society.