Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon?

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Kavanagh D., Pappworth I. Y., Anderson H., Hayes C. M., Moore I., Hunze E., ...Daha Fazla

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, cilt.7, sa.3, ss.417-426, 2012 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 7 Sayı: 3
• Basım Tarihi: 2012
• Doi Numarası: 10.2215/cjn.05750611
• Dergi Adı: CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.417-426
• Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background and objectives Atypical hemolytic uremic syndrome is a disease associated with mutations in the genes encoding the complement regulators factors H and I. In addition, factor H autoantibodies have been reported in similar to 10% of patients with atypical hemolytic uremic syndrome. This study searched for the presence of factor 1 autoantibodies in atypical hemolytic uremic syndrome.