Effects of Stimulants on Sleep Parameters With Attention Deficit Hyperactivity Disorder

Turan S., Akay A.

Eurasian Journal of Medical Investigation, cilt.4, sa.3, ss.341-346, 2020 (TRDizin)

Özet

Objectives: This study aims to evaluate the effects of methylphenidate (MPH) on sleep parameters and BMI in attention-deficit/hyperactivity disorder (ADHD) children.Methods: Eighty five ADHD children were enrolled and daily sleep diaries were evaluated after taking medication. Thiscross-sectional case-control study also included ninety five healthy children. BMI Z scores were measured at baselineand at last follow-up.Results: Eighty five patients (mean [standard deviation] age: 14,02 [±1.6] years, 65 (77%) males) were included. Whenwe compared ADHD and healthy control group, we observed significant statistical difference between two groups onthe mean total scores of CSHQ and PSQI (p<0.05). For CSHQ, subscales about sleep delay, sleep duration and daytimesleepiness are also significantly higher in ADHD group (p<0.05). For PSQI, subscales about sleep disturbance, sleeplatency and subjective sleep quality differed significantly. MPH treatment was associated with a notional reduction inbody mass index standard deviation scores (SDS).Conclusion: These findings indicate children with ADHD under stimulant treatment experience more sleep problemsthan healthy peers accorrding to both self and parent reports. MPH slightly descreased BMI-sds in this group of ADHDpatients followed naturalistically over 32.2 months.