Mesangial C4d deposition is independently associated with poor renal survival in patients with primary focal segmental glomerulosclerosis

Heybeli, CİHAN; Oktan, MEHMET; Yildiz, Serkan; Unlu, Mehtat; Celli, Ali; SARIOĞLU, SÜLEN

doi:10.1007/s10157-018-01688-0

Mesangial C4d deposition is independently associated with poor renal survival in patients with primary focal segmental glomerulosclerosis

Heybeli C., Oktan M. A., Yildiz S., Unlu M., Celli A., SARIOĞLU S.

CLINICAL AND EXPERIMENTAL NEPHROLOGY, vol.23, no.5, pp.650-660, 2019 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 23 Issue: 5
Publication Date: 2019
Doi Number: 10.1007/s10157-018-01688-0
Journal Name: CLINICAL AND EXPERIMENTAL NEPHROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.650-660
Keywords: Complement C4d, Focal segmental glomerulosclerosis, IgM, Mannan-binding lectin
Dokuz Eylül University Affiliated: Yes

Abstract

Background C4d deposition is defined as the footprint of immune injury and it is associated with unfavorable renal outcomes in patients with IgA nephropathy. We searched whether mesangial C4d deposition is associated with poor renal survival in patients with primary focal segmental glomerulosclerosis (FSGS).