Mesangial C4d deposition is independently associated with poor renal survival in patients with primary focal segmental glomerulosclerosis

Heybeli C., Oktan M. A., Yildiz S., Unlu M., Celli A., SARIOĞLU S.

CLINICAL AND EXPERIMENTAL NEPHROLOGY, cilt.23, sa.5, ss.650-660, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/s10157-018-01688-0
  • Dergi Adı: CLINICAL AND EXPERIMENTAL NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.650-660
  • Anahtar Kelimeler: Complement C4d, Focal segmental glomerulosclerosis, IgM, Mannan-binding lectin, COMPLEMENT PATHWAY, IGA NEPHROPATHY, LECTIN PATHWAY, C3
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background C4d deposition is defined as the footprint of immune injury and it is associated with unfavorable renal outcomes in patients with IgA nephropathy. We searched whether mesangial C4d deposition is associated with poor renal survival in patients with primary focal segmental glomerulosclerosis (FSGS).