Research Information System
The 54th Annual Congress of the International Society of Paediatric Oncology, Barcelona, Spain, 28 September - 01 October 2022, pp.1566
Background and Aims
AYA (Adolescents and Young Adults) includes 15 to 39 years of age. Over 70000 AYAs are diagnosed with cancer each year in United States. Adolescent cancers are defined as cancers between 15-19 years of age and only this group can be treated and followed in pediatric oncology. We aimed to present our adolescent patients in this study.
Methods
A retrospective review of 209 patients between 15-19 years of age at diagnosis was done. Medical files were evaluated for distribution of cancer types, clinical features, treatment courses, survival rates and follow-up times.
Results
Two hundred and nine patients between 15-19 years, who diagnosed with lymphoma and solid tumors at our department in the last 34 years evaluated. The median age at diagnosis was 16.3 yrs. M/F: 1.2 (115/94). Cancer type distribution was as follows: Hodgkin lymphoma (20.6%), NHL (16.3%), CNS tm (13.4%), nonrhabdo sarcoma (10%), germ cell tm (9.6%), Ewing sarcoma (7.2%), osteosarcoma (6.7%), others (%16.2). Treatment details as follows: Chemotherapy (22%), chemotherapy+radiotherapy (24.4%), chemotherapy+radiotherapy+surgery (19.1%), chemotherapy+surgery (19.1%), radiotherapy+surgery (5.8%), surgery (9.6%). Median follow-up time was 36 mos (1mos-28yrs). Non-compliance to treatment was observed in 8% of patients. Overall survival was 71% and event-free survival was 51% for 5 years.
Conclusions
Adolescent cancer patients are different from younger group. Their
treatment begins in pediatric oncology department but after 18 years of age, it
continues in adult clinics. As solution, treatment centers special for AYA
patients should be considered.