Influence of menthol on caffeine disposition and pharmacodynamics in healthy female volunteers

Creative Commons License

Gelal A., Guven H., Balkan D., Artok L., Benowitz N.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, cilt.59, ss.417-422, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1007/s00228-003-0631-1
  • Dergi Adı: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.417-422
  • Anahtar Kelimeler: menthol, caffeine, monoterpenes, PEPPERMINT OIL, BLOOD-PRESSURE, RAT-LIVER, IN-VITRO, CYTOCHROME-P-450, PHARMACOLOGY, 1,8-CINEOLE, METABOLISM
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives. The present study was undertaken to determine whether a single oral dose of menthol affects the metabolism of caffeine, a cytochrome P-450 1A2 (CYP1A2) substrate, and pharmacological responses to caffeine in people.