Torsades de pointes with a severely prolonged QT interval induced by an initial low dose sotalol intake

Yalta K., TURGUT O. O., YILMAZ A., YILMAZ M. B., Kendirlioglu O., Karadas F.

International Journal of Cardiology, cilt.116, sa.3, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.ijcard.2006.08.091
  • Dergi Adı: International Journal of Cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: QT interval, Sotalol, Torsades de pointes
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Many drugs, including sotalol, have been implicated in prolonging QT interval and triggering torsades de pointes, a potentially fatal ventricular arrhythmia, especially during chronic therapy or in case of acute high dose toxicity. We report here a case with a severely prolonged QT interval and torsades de pointes after an initial intake of low dose sotalol (80 mg), indicating a probable inherent individual oversensitivity to sotalol. © 2006 Elsevier Ireland Ltd. All rights reserved.