Torsades de pointes with a severely prolonged QT interval induced by an initial low dose sotalol intake
International Journal of Cardiology, vol.116, no.3, 2007 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 116 Issue: 3
- Publication Date: 2007
- Doi Number: 10.1016/j.ijcard.2006.08.091
- Journal Name: International Journal of Cardiology
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: QT interval, Sotalol, Torsades de pointes
- Dokuz Eylül University Affiliated: Yes
Abstract
Many drugs, including sotalol, have been implicated in prolonging QT interval and triggering torsades de pointes, a potentially fatal ventricular arrhythmia, especially during chronic therapy or in case of acute high dose toxicity. We report here a case with a severely prolonged QT interval and torsades de pointes after an initial intake of low dose sotalol (80 mg), indicating a probable inherent individual oversensitivity to sotalol. © 2006 Elsevier Ireland Ltd. All rights reserved.