Farelerde Yüksek Doz İsotretinoin Uygulamasının Yol Açtığı Kalp Dokusu Hasarına Karşı Silymarinin Olası Etkilerinin Araştırılması
Bezmiâlem Science, vol.4, no.2, pp.43-50, 2016 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 4 Issue: 2
- Publication Date: 2016
- Doi Number: 10.14235/bs.2016.682
- Journal Name: Bezmiâlem Science
- Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Page Numbers: pp.43-50
- Keywords: Isotretinoin, silymarin, heart, oxidative stress, apoptosis, histopathology
- Dokuz Eylül University Affiliated: No
Abstract
Objective: We aimed to histopathologically and biochemically investigate the protective effects of silymarin (SLY) against cardiac injury induced by a high-dose isotretinoin (ISR) administration.