Exchange transfusion treatment in a newborn with phenobarbital intoxication


Sancak R., Kücüködük S., Tasdemir H., BELET N.

PEDIATRIC EMERGENCY CARE, cilt.15, sa.4, ss.268-270, 1999 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1097/00006565-199908000-00010
  • Dergi Adı: PEDIATRIC EMERGENCY CARE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.268-270
  • Anahtar Kelimeler: phenobarbital intoxication, newborn, exchange transfusion
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

A comatose, M-day-old bog was referred to our emergency department (ED) after an overdose of phenobarbital, which was used for the treatment of long-standing jaundice. Plasma phenobarbital concentration was 112.4 mu g/ml before treatment. One hour after giving albium transfusion, an exchange transfusion, which took about 45 minutes, was performed. Volume of exchange was 400 mi (volume of exchange (ml) = 2 x 85 ml/kg), After the exchange transfusion, the phenobarbital concentration decreased to 50.84 mu g/ml. At clinical and laboratory followup, the patient recovered fully. This case suggests that exchange transfusion is an effective and successful treatment for phenobarbital intoxication in newborn.