Silent brain infarcts: A cause of depression in the elderly?

Perez H. C. S., Direk N., Hofman A., Vernooij M. W., Tiemeier H., Ikram M. A.

PSYCHIATRY RESEARCH-NEUROIMAGING, vol.211, no.2, pp.180-182, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 211 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1016/j.pscychresns.2012.06.005
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.180-182
  • Keywords: Silent brain infarcts, Recurrent depression, Incident depression, MAJOR DEPRESSION
  • Dokuz Eylül University Affiliated: No


The present study included 1047 elderly participants. At baseline, brain magnetic resonance imaging (MRI) was performed to detect infarcts and white matter lesions; further, depressive disorders were assessed. Participants were followed up during 3.6 years to determine incident and recurrent depression. We found an increased risk of recurrent depression associated with silent brain infarcts. (C) 2012 Elsevier Ireland Ltd. All rights reserved.