The relationship between changes in peritoneal membrane solute transfer characteristics and cardiac remodeling in patients with peritoneal dialysis

Oktan M. A., Korucu B., Çolak A., Bildacı Y., Çavdar C., Değer S. M.

Therapeutic Apheresis and Dialysis, cilt.28, sa.6, ss.871-879, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 6
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1111/1744-9987.14170
  • Dergi Adı: Therapeutic Apheresis and Dialysis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, MEDLINE
  • Sayfa Sayıları: ss.871-879
  • Anahtar Kelimeler: atrial dilatation, peritoneal dialysis, peritoneal membrane solute transfer characteristics, ventricle dilatation
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: We aimed to determine the relationship between the dilatation of the heart chambers and the change in peritoneal membrane solute transfer characteristics (PMTC) in long-term peritoneal dialysis (PD) patients. Methods: This is a retrospective, single-center study including the follow-up of maintenance PD patients. According to the changes in PMTC from baseline to the last visit, patients were divided into three groups; stable (n = 11), increased (n = 41), and decreased transporters (n = 35). Results: Left atrium (LA) and Right ventricle (RV) dilatation were more prominent in the PMTC-decreased group compared to PMTC-increased and stable groups (p < 0.001 and p = 0.07, respectively). The Cox regression analysis showed that only decreased PMTC was associated with LA dilatation (HR 2.89 [CI 95%1.54, 5.45] p < 0.01) and RV dilatation (HR 3.01 [CI 95%1.40, 6.21] p < 0.01). Conclusion: PD can be associated with unfavorable dynamic changes in cardiac structure and functions even at the subclinical level.