Antiproliferative Effects of Carvacrol on Neuroblastoma Cells

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ÇALIBAŞI KOÇAL G., Pakdemirli A.

IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI, cilt.10, sa.1, ss.61-64, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5222/buchd.2020.59251
  • Dergi Adı: IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.61-64
  • Anahtar Kelimeler: Carvacrol, neuroblastoma, proliferation, pediatric cancers, PROLIFERATION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Neuroblastoma is a pediatric solid tumor that originates from the neural crest. The survival rate of these malignancies is below 50 %. The most common treatments for the disease have several adverse effects which make them invasive for patients and limits the applicability as well as continuity of the treatment. Therefore, researchers seek new agents to reduce adverse effects in order to improve the treatment. In this wise, plant-derived phytochemicals are promising drug candidates, such as carvacrol which has anti-cancer features in some cancers.