Antiproliferative Effects of Carvacrol on Neuroblastoma Cells


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ÇALIBAŞI KOÇAL G., Pakdemirli A.

IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI, vol.10, no.1, pp.61-64, 2020 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.5222/buchd.2020.59251
  • Journal Name: IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.61-64
  • Keywords: Carvacrol, neuroblastoma, proliferation, pediatric cancers, PROLIFERATION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Neuroblastoma is a pediatric solid tumor that originates from the neural crest. The survival rate of these malignancies is below 50 %. The most common treatments for the disease have several adverse effects which make them invasive for patients and limits the applicability as well as continuity of the treatment. Therefore, researchers seek new agents to reduce adverse effects in order to improve the treatment. In this wise, plant-derived phytochemicals are promising drug candidates, such as carvacrol which has anti-cancer features in some cancers.