Exposure to Fumes of a Vegetable Margarine for Frying: Respiratory Effects in an Experimental Model


Çımrın A. H., Özgen Alpaydın A., Özbal S., Toprak M., Yılmaz O., Uluorman F., ...Daha Fazla

ACS OMEGA, cilt.8, sa.35, ss.31880-31889, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 35
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1021/acsomega.3c03340
  • Dergi Adı: ACS OMEGA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
  • Sayfa Sayıları: ss.31880-31889
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Deep frying is oneof the strongest emission sources into indoorair. A vegetable margarine has recently been used in commercial kitchens.This study investigated the respiratory effects of exposure to itsfumes in an experimental model. A setup with glass chambers was constructed.A chamber housed a fryer. The fumes were transported to the otherchamber where 24 Wistar albino rats were placed in four randomizedgroups: acute, subacute, chronic, and control for the exposure durations.PM10 concentration in the exposure chamber was monitoredto ensure occupational levels were obtained. Sacrification was performed24 h after exposure. Lung, trachea, and nasal concha specimens wereevaluated by two blinded histologists under a light microscope withhematoxylin-eosin. Mild mononuclear cell infiltration, alveolarcapillary membrane thickening, alveolar edema, and diffuse alveolardamage, along with diffuse hemorrhage, edema, and vascular congestionin the interstitium were observed in the acute and subacute groups,and were overexpressed in the chronic group, whereas normal lung histologywas observed in the control group. The results indicate that exposureto fumes of vegetable margarine for frying in commercial kitchensmay cause pulmonary inflammation that becomes severe as the durationof the exposure increases.