Hashimoto's thyroiditis, but not treatment of hypothyroidism, is associated with altered TGF-beta1 levels.

AKINCI B., ÇÖMLEKÇİ A., Yener S., BAYRAKTAR F., DEMİR T., ÖZCAN M. A., ...Daha Fazla

Archives of medical research, cilt.39, sa.4, ss.397-401, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.arcmed.2007.12.001
  • Dergi Adı: Archives of medical research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.397-401
  • Anahtar Kelimeler: thyroiditis, autoimmunity, cytokine, transforming growth factor beta, GROWTH-FACTOR-BETA, TRANSFORMING GROWTH-FACTOR-BETA-1, TGF-BETA, AUTOIMMUNE-THYROIDITIS, FOLLICULOGENESIS, EXPRESSION, CYTOKINE, FIBROSIS, CELLS, SERUM
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background. Although the role of cytokines in the development of Hashimoto's thyroiditis has already been established, its pathogenesis has not yet been clearly elucidated. The aim of our study was to investigate serum transforming growth factor-beta 1 (TGF-beta 1) levels in patients with Hashimoto's thyroiditis as well as the effect of achieving euthyroidism by levothyroxine replacement on TGF-beta 1 levels.