Dapsone as an Alternative Therapy in Children with Familial Mediterranean Fever
IRANIAN JOURNAL OF PEDIATRICS, vol.22, no.1, pp.23-27, 2012 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 22 Issue: 1
- Publication Date: 2012
- Journal Name: IRANIAN JOURNAL OF PEDIATRICS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.23-27
- Keywords: Dapsone, Familial Mediterranan Fever, Periodic Fever, Children
- Dokuz Eylül University Affiliated: No
Abstract
Objective: Familial Mediterranan Fever is an hereditary autoinflammatory disease that presents with recurrent febrile attacks and poly serositis. Colchicine is the only known treatment in this diease. However, nearly 5-10% of patients are resistant to colchicines. There are many different modalities in colchicine resistant patients, biologic and immunosupressive drugs being the known ones. We studied the efficacy of Dapsone as an anti inflammatory drug in children with FMF who did not tolerate colchicine well.