In this study, towing tank experiments have been carried out for a container ship under different trim-draft conditions. Experimental results have been interpreted together with the results of the Holtrop method used in both Maxsurf and Orca to identify reactions to changing trim conditions. The study has shown that towing tank experiment findings differ from other relevant findings. The ship shows different resistance characteristics under different trim conditions, but generally the least resistance without trim. In addition, the total resistance change at ship design speed was found to be up to 18% higher in the trim by aft condition. We believe that study findings will help better understand the constantly changing resistance variable depending on draft, speed, and trim conditions.