Human beta defensin-1 and -2 expression in the gingiva of patients with specific periodontal diseases

Vardar-Sengul S., Demirci T., Sen B. H., Erkizan V., Kurulgan E., Baylas H.

JOURNAL OF PERIODONTAL RESEARCH, cilt.42, sa.5, ss.429-437, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1600-0765.2006.00964.x
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.429-437
  • Anahtar Kelimeler: defensin, gingiva, gingivitis, periodontitis, real-time polymerase chain reaction
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background and Objective: beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingivitis, aggressive periodontitis and chronic periodontitis, and to evaluate the relationship between defensin expression and type and/or severity of periodontal destruction.