Berberine Attenuates Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage Via Modulating AMPK/Rho Pathway

Kadirhan O. A., Kumaş M., Karatas E., Mutlu H. S., Koçyiğit A., Asil T.

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.4, no.3, pp.310-317, 2020 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.30621/jbachs.2020.1125
  • Journal Name: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.310-317
  • Keywords: berberine, subarachnoid hemorrhage, cerebral vasospasm, AMP-Activated Protein Kinase, Rho kinase, endothelial dysfunction, ACTIVATED PROTEIN-KINASE, EARLY BRAIN-INJURY, NITRIC-OXIDE SYNTHASE, BARRIER DISRUPTION, RHO-KINASE, MECHANISMS, INHIBITION, CINGULIN, ARTERIES, NOX4
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: Our goal is to clarify the effectiveness of berberine (BBR) on cerebral vasospasm induced by subarachnoid hemorrhage.