Bilateral primary orbital non-Hodgkin's lymphoma in a patient with scleroderma: a case report.

Alacacioglu İ., Ozcan M., Kocak N., Demiral A. N., Piskin O., DEMİRKAN F., ...Daha Fazla

Leukemia & lymphoma, cilt.46, sa.8, ss.1239-42, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 8
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/10428190500097748
  • Dergi Adı: Leukemia & lymphoma
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1239-42
  • Anahtar Kelimeler: NHL, orbital lymphoma, scleroderma, RADIOTHERAPY, TUMORS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Orbital presentation of non-Hodgkin's Lymphoma (NHL) is uncommon but occurs both as the only site of disease and as a site of recurrence. Primary orbital NHLs are usually low-grade, and mostly extranodal marginal zone/mucosa associated lymphoid tissue B-cell neoplasms. They are commonly associated with chronic inflammatory conditions. The issue of bilaterality in orbital lymphoma is not very common. The onset of malignant lymphoproliferation may precede, follow, or exist simultaneously with scleroderma. Different treatment modalities were applied in orbital NHL such as surgery, radiation therapy, chemotherapy or both. We report a 57-year-old man with scleroderma presenting with eyelid hernias who had biopsy-proven marginal zone NHL, successfully treated with radiotherapy and combined chemotherapy, and also review the literature.