Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model


Mas M. R., IŞIK A. T., Yamanel L., Inal V., Tasci I., Deveci S., ...Daha Fazla

PANCREAS, cilt.33, sa.1, ss.77-81, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1097/01.mpa.0000222316.74607.07
  • Dergi Adı: PANCREAS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.77-81
  • Anahtar Kelimeler: chronic pancreatitis, pancreatic fibrosis, experimental pancreatitis, oxidative stress, antioxidants, taurine, LIPID-PEROXIDATION, STELLATE CELLS, OXIDATIVE STRESS, LIVER, ACTIVATION, FIBROSIS
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objectives: Based on the results of recent studies that reported depleted antioxidant capacity in patients with chronic pancreatitis (CP), prevention of free radical production has gained importance in antifibrotic treatment strategies in CP. The aim of this study was to investigate the effects of taurine on oxidative capacity and fibrosis in experimental chronic rat pancreatic fibrosis.