Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model

Mas M. R., IŞIK A. T., Yamanel L., Inal V., Tasci I., Deveci S., ...More

PANCREAS, vol.33, no.1, pp.77-81, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1097/01.mpa.0000222316.74607.07
  • Journal Name: PANCREAS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-81
  • Keywords: chronic pancreatitis, pancreatic fibrosis, experimental pancreatitis, oxidative stress, antioxidants, taurine, LIPID-PEROXIDATION, STELLATE CELLS, OXIDATIVE STRESS, LIVER, ACTIVATION, FIBROSIS
  • Dokuz Eylül University Affiliated: No

Abstract

Objectives: Based on the results of recent studies that reported depleted antioxidant capacity in patients with chronic pancreatitis (CP), prevention of free radical production has gained importance in antifibrotic treatment strategies in CP. The aim of this study was to investigate the effects of taurine on oxidative capacity and fibrosis in experimental chronic rat pancreatic fibrosis.