A patient with diffuse large B-cell non-Hodgkin's lymphoma and AA type amyloidosis

Piskin O., Alacacioglu İ., Ozkal S., Ozcan M. A., DEMİRKAN F., ÖZSAN G. H., ...Daha Fazla

JOURNAL OF BUON, cilt.13, sa.1, ss.113-116, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 1
  • Basım Tarihi: 2008
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.113-116
  • Anahtar Kelimeler: AA amyloidosis, amyloidosis, diabetes mellitus type 2, diffuse large B-cell lymphoma, non-Hodgkin's lymphoma
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

AA-type amyloidosis is a consequence of a long-standing systemic inflammation and is not associated with a monoclonal protein or clonal bone marrow plasma cells. Pro-inflammatory cytokines such as interleukin (IL)1, IL-6, and tumor necrosis factor (TNF) stimulate the synthesis of serum amyloid A during inflammation. Although the association of non-Hodgkin's lymphoma (NHL) with AL-type amyloidosis is well known and patients with Hodgkin lymphoma with AA amyloidosis have been described, AA-type amyloidosis with NHL is extremely infrequent. We report a case of amyloidosis associated with NHL that subsided during R-CHOP chemotherapy.