A patient with diffuse large B-cell non-Hodgkin's lymphoma and AA type amyloidosis
JOURNAL OF BUON, cilt.13, sa.1, ss.113-116, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 1
- Basım Tarihi: 2008
- Dergi Adı: JOURNAL OF BUON
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.113-116
- Anahtar Kelimeler: AA amyloidosis, amyloidosis, diabetes mellitus type 2, diffuse large B-cell lymphoma, non-Hodgkin's lymphoma
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
AA-type amyloidosis is a consequence of a long-standing systemic inflammation and is not associated with a monoclonal protein or clonal bone marrow plasma cells. Pro-inflammatory cytokines such as interleukin (IL)1, IL-6, and tumor necrosis factor (TNF) stimulate the synthesis of serum amyloid A during inflammation. Although the association of non-Hodgkin's lymphoma (NHL) with AL-type amyloidosis is well known and patients with Hodgkin lymphoma with AA amyloidosis have been described, AA-type amyloidosis with NHL is extremely infrequent. We report a case of amyloidosis associated with NHL that subsided during R-CHOP chemotherapy.