Beyond skeletal-related events

Kirkali Z.

EUROPEAN UROLOGY SUPPLEMENTS, cilt.5, sa.7, ss.553-555, 2006 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 7
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.eursup.2006.02.029
  • Dergi Adı: EUROPEAN UROLOGY SUPPLEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.553-555
  • Anahtar Kelimeler: antitumor, clinical trials, preclinical, prostate cancer, zoledronic acid, IN-VITRO, BISPHOSPHONATES, PROSTATE, BONE
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objectives: Zoledronic acid may have potential antitumor activity; it is the most active agent among the bisphosphonates in blocking the prenylation (activation) of small signaling proteins required for cell function and survival. This presentation discusses the results of preclinical studies evaluating the antitumor activity of zoledronic acid and discusses initiated clinical studies.