A patient with renal osteodystrophy developing severe secondary hyperparathyroidism during growth hormone therapy Büyüme hormonu tedavisi sirasinda aǧir sekonder hiperparatiroidizm bulgulari gelişen bir renal osteodistrofi vakasi

SOYLU A., SUNNELI L., Türkmen M., Büyükgebiz A., KAVUKÇU S.

Cocuk Sagligi ve Hastaliklari Dergisi, cilt.45, sa.1, ss.65-68, 2002 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 1
  • Basım Tarihi: 2002
  • Dergi Adı: Cocuk Sagligi ve Hastaliklari Dergisi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.65-68
  • Anahtar Kelimeler: Chronic renal failure, Growth hormone, Secondary hyperparathyroidiSm
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Severe secondary hyperparathyroidism has been reported to develop in children with chronic renal failure treated with recombinant human growth hormone due to growth retardation. We report here a 15-year-old-boy undergoing a chronic hemodialysis program who developed severe secondary hyperparathyroidism within nine months of recombinant human growth hormone therapy. His alkaline phosphatase and parathormone levels increased progressively during therapy (2749 IU/L, 425 pg/ml, respectively). After discontinuation of growth hormone treatment at 12th month due to insufficient height velocity, and administration of high dose calcitriol, his alkaline phosphatase and parathormore levels decreased within four months.