Drug reaction to ursodeoxycholic acid: Lichenoid drug eruption in an infant using ursodeoxycholic acid for neonatal hepatitis

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Buyukgebiz B., Arslan N., Ozturk Y., Soyal C., Lebe B.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, vol.35, no.3, pp.384-386, 2002 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 35 Issue: 3
• Publication Date: 2002
• Doi Number: 10.1097/01.mpg.0000024324.70265.03
• Journal Name: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.384-386
• Keywords: lichenoid eruptions, infant, ursodeoxycholic acid, PLANUS
• Dokuz Eylül University Affiliated: Yes

Abstract

Lichenoid drug eruptions are skin reactions associated With a number of drugs and chemicals. They are rare in infants. We report here an infant who presented with neonatal hepatitis and who was being treated with ursodeoxycholic acid. The infant developed lichenoid skin eruptions in the third week of the therapy. The lesions have resolved two months after the discontinuation of the drug. To our knowledge, this is the first infant case of lichenoid drug eruption associated with ursodeoxycholic acid.