Black joint and synovia: Histopathological evaluation of degenerative joint disease due to Ochronosis

Doganavsargil B., Pehlivanoglu B., KAYA BİÇER M. E., ARGIN M., Bingul K. B., SEZAK M., ...More

PATHOLOGY RESEARCH AND PRACTICE, vol.211, no.6, pp.470-477, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 211 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1016/j.prp.2015.03.001
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.470-477
  • Keywords: Alkaptonuria, Ochronosis, Degenerative joint diseases, Ochronotic arthropathy, Synovitis, ALKAPTONURIA, ARTHROPATHY, PATIENT, MODEL
  • Dokuz Eylül University Affiliated: No

Abstract

Introduction: Ochronotic arthropathy is a rapidly progressive and disabling arthropathy predominantly encountered after the fifth decade of life, caused by homogentisate1,2 dioxygenase enzyme deficiency. As it is rare disease, the literature on histological findings is fragmented.