Childhood Malign Solid Soft Tissue Sarcomas; Diagnostic, Histopathological and Molecular Approach

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Yildirim H. T., Yildirim A., Diniz G., AKTAŞ S., Vergin C.

IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI, cilt.9, sa.1, ss.1-9, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5222/buchd.2019.98698
  • Dergi Adı: IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1-9
  • Anahtar Kelimeler: Childhood, solid soft tissue tumors, diagnostic approach, differential diagnosis, ROUND-CELL TUMORS, IMMUNOHISTOCHEMISTRY, PITFALL
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Childhood soft tissue sarcomas are heterogenous and be quite varied in apperance. Especially, these neoplasms known as "small round cell tumor" group, with their hyperchromatic nuclei and monotonous small and limited cytoplasm. These neoplasms share many similar histomorphological and immunophenotypic characteristics Also these lesions may often demonstrate similar clinical and radiological characteristics but have diverse prognoses. The purpose of this article is to review clinical, histologic, immunohistochemical features and molecular features of soft tissue sarcomas and discuss the differential diagnosis of these tumours.