The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study

ŞIKLAR, ZEYNEP; Genens, Mikayir; Poyrazoglu, Sukran; BAŞ, Firdevs; Darendeliler, Feyza; Bundak, Ruveyde; Aycan, Zehra; Erdeve, Senay; Cetinkaya, Semra; Guven, Ayla; ABALI, Saygın; Atay, Zeynep; DEMİRCİOĞLU, SERAP; Kara, Cengiz; Yilmaz, Gulay; Akyurek, Nesibe; ABACI, AYHAN; Celmeli, Gamze; Sari, Erkan; Bolu, Semih; Korkmaz, Huseyin; Simsek, Enver; Catli, Gonul; Buyukinan, Muammer; Cayir, Atilla; EVLİYAOĞLU, Saadet; Isguven, Pinar; ÖZGEN, İLKER; HATİPOĞLU, NİHAL; ELHAN, ATİLLA; BERBEROĞLU, MERİH

doi:10.4274/jcrpe.3013

The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study

ŞIKLAR Z., Genens M., Poyrazoglu S., BAŞ F., Darendeliler F., Bundak R., ...More

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.8, no.3, pp.305-312, 2016 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 8 Issue: 3
Publication Date: 2016
Doi Number: 10.4274/jcrpe.3013
Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.305-312
Keywords: Noonan syndrome, growth hormone treatment, growth
Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Noonan syndrome (NS) is a multisystem disorder, and short stature is its most striking manifestation. Optimal growth hormone (GH) treatment for NS is still controversial. In this study, using a nationwide registration system, we aimed to evaluate the growth characteristics and the clinical features of NS patients in Turkey and their growth response to GH treatment.