Intracerebroventricular injection of histamine induces the hypothalamic-pituitary-gonadal axis activation in male rats


Niaz N., Guvenc G., Altinbas B., Toker M. B., Aydin B., Udum-Kucuksen D., ...More

BRAIN RESEARCH, vol.1699, pp.150-157, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1699
  • Publication Date: 2018
  • Doi Number: 10.1016/j.brainres.2018.08.020
  • Journal Name: BRAIN RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.150-157
  • Keywords: Histamine, Central histaminergic receptors, Hypothalamic-pituitary-gonadal axis, Sperm parameters, Intracerebroventricular, CRITICAL HEMORRHAGIC HYPOTENSION, FOLLICLE-STIMULATING-HORMONE, LUTEINIZING-HORMONE, GONADOTROPIN-SECRETION, RECEPTOR SUBTYPES, BETA-ENDORPHIN, SPERM QUALITY, LEYDIG-CELL, DANISH MEN, TESTOSTERONE
  • Dokuz Eylül University Affiliated: No

Abstract

Brain histamine holds a key position in the regulation of behavioral states, biological rhythms, body weight, energy metabolism, thermoregulation, fluid balance, stress and reproduction in female animals. However, it is not clear whether central histamine exerts any effect on hypothalamic-pituitary-testicular in male rats and if so, the involvement of type of central histamine receptors.