Comparison of TNF antagonism by etanercept and dexamethasone on airway epithelium and remodeling in an experimental model of asthma

YILMAZ Ö., KARAMAN M., BAĞRIYANIK H. A., Firinci F., KİRAY M., Turkeli A., ...Daha Fazla

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.17, sa.3, ss.768-773, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.intimp.2013.08.021
  • Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.768-773
  • Anahtar Kelimeler: Mouse model of asthma, Remodeling, Inflammation, Tumor necrosis factor, Steroid, TUMOR-NECROSIS-FACTOR, SMOOTH-MUSCLE, FACTOR-ALPHA, ADHESION MOLECULES, BASEMENT-MEMBRANE, DOUBLE-BLIND, INFLAMMATION, MODULATION, ALLERGEN, EXPRESSION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: The aim of the study was to compare the influence of TNF antagonism and corticosteroid treatment on epithelial, smooth muscle and basement membrane component of airway remodeling in an experimental murine model of chronic asthma.