Effects of sulthiame on seizure frequency and EEG in children with electrical status epilepticus during slow sleep

Topcu Y., Kilic B., Tekin H. G., Aydin K., Turanli G.

EPILEPSY & BEHAVIOR, vol.116, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116
  • Publication Date: 2021
  • Doi Number: 10.1016/j.yebeh.2021.107793
  • Journal Name: EPILEPSY & BEHAVIOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE, Psycinfo
  • Keywords: Sulthiame, Electrical status epilepticus during slow sleep, EEG, Seizure, Children
  • Dokuz Eylül University Affiliated: No

Abstract

Objective: It is argued that early and adequate treatment of electrical status epilepticus in sleep (ESES) is essential to preserve cognitive functions and possibly recovering lost skills. Although antiepileptic drugs (AEDs) are effective in ESES, there is not much experience in the use of sulthiame. In this study, we aimed to examine the efficiency and tolerability of sulthiame in ESES.