CYTOGENETIC FINDINGS IN 19 MALIGNANT BONE TUMORS


OZISIK Y., MELONI A., PEIER A., ALTUNGOZ O., SPANIER S., ZALUPSKI M., ...More

CANCER, vol.74, no.8, pp.2268-2275, 1994 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 8
  • Publication Date: 1994
  • Journal Name: CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2268-2275
  • Keywords: CYTOGENETICS, KARYOTYPES, OSTEOSARCOMA, CHONDROSARCOMA, OSTEO-SARCOMA, P53 GENE, CHROMOSOME REARRANGEMENTS, MYXOID CHONDROSARCOMA, TISSUE TUMORS, SOFT-TISSUE, OSTEOSARCOMA, TRANSLOCATIONS, ABNORMALITIES, AMPLIFICATION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background. The majority of karyotypes observed in osteosarcomas (OS) and chondrosarcomas (CS) are complex. Specific chromosomal abnormalities have not yet been characterized in either tumor except for a ring chromosome in parosteal OS. The purpose of this study was to determine recurrent chromosomal abnormalities and establish a possible correlation between the cytogenetic changes and the pathologic findings.