Akademik Veri Yönetim Sistemi
Endoskopi, sa.20, ss.13-16, 2012 (TRDizin)
Girifl ve Amaç: Çal›flman›n amac› endoskopist ve patologlar›n üst gastrointestinal mukoza tan›lar› aras›ndaki uyumu araflt›rmak ve endoskopik ve patolojik tan›lara göre Helikobakter pilori s›kl›¤›n› belirlemekdir. Gereç ve Yöntem: Çal›flmaya Celal Bayar Üniversitesi T›p Fakültesi Gastroenteroloji klini-
¤inde Haziran 2008-Haziran 2010 y›llar› aras›nda üst gastrointestinal sistem
endoskopisi ve biyopsisi yap›lan 1597 olgu retrospektif incelenerek dahil
edilmifltir. Bulgular: Endoskopik olarak normal bulunan olgular›n patolojik
olarak normal de¤erlendirilmesinde özgüllük %86.8, duyarl›l›k %30.8, pozitif prediktif de¤er %19.4 ve negatif prediktif de¤er %92.4, endoskopik olarak
gastrit de¤erlendirilen olgular›n patolojik olarak da gastrit olarak de¤erlendirilmesinde özgüllük %30.8, duyarl›l›k %85.3, pozitif prediktif de¤er %89.6
ve negatif prediktif de¤er %23.1, endoskopik olarak malign de¤erlendirilen
olgularda patolojik olarak da malign de¤erlendirilmede özgüllük %99.1, duyarl›l›k %96.4, pozitif prediktif de¤er %84.3 ve negatif prediktif de¤er %99.8
olarak bulunmufltur. Helikobakter pilori %40 olguda pozitif olarak saptanm›flt›r. Sonuç: Her ne kadar endoskopistlerin malinite ve gastrit olarak de¤erlendirdikleri olgular tan› olarak patologlar ile uyumlu olsa da yaln›zca bu
gruplardan de¤il mutlaka endoskopik olarak normal nitelendirilen olgulardan da biyopsi al›nmas› önerilir.
Background/aims: The aim of this study was to evaluate retrospectively the
consistency of the diagnoses by endoscopists and pathologists, to determine
whether the endoscopic diagnosis is adequate, and to compare the endoscopic and pathological diagnoses of Helicobacter pylori. Materials and Methods: 1597 subjects who underwent an upper endoscopy and an endoscopic
biopsy (antrum and corpus) were recruited retrospectively from Celal Bayar
University Gastroenterology Department in Manisa, Turkey between January
2008 and January 2010. Results: The specificity was 86.8%, sensitivity
30.8%, positive predictive value 19.4%, and negative predictive value 92.4%
between the endoscopically normal and pathologically normal cases. The specificity was 30.8% and sensitivity 85.3%, with a positive predictive value of
89.6% and a negative predictive value of 23.1% between gastritis shown endoscopically versus pathologically. The specificity was 99.1% and sensitivity
96.4%, with a positive predictive value of 84.3% and negative predictive value of 99.8%, between malignancy shown endoscopically versus pathologically. Helicobacter pylori was positive in 653 (40%) patients. Conclusions:
Although the endoscopic and pathological diagnoses were compatible, especially when examining malignancy and gastritis, and despite the fact that the
endoscopic evaluations of the upper gastrointestinal system were deemed to
be normal, a biopsy is still recommended.