Metabolic and cardiovascular impact of non-functioning adrenal adenomas: a clinical dilemma.

Yener S.

European journal of internal medicine, vol.24, no.6, pp.520-4, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1016/j.ejim.2013.02.005
  • Journal Name: European journal of internal medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.520-4
  • Keywords: Non-functioning adrenal adenoma, Metabolic syndrome, Cardiovascular disease, SUBCLINICAL CUSHINGS-SYNDROME, GLUCOCORTICOID-RECEPTOR GENE, TERM-FOLLOW-UP, RISK-FACTORS, INSULIN-RESISTANCE, TURKISH ADULTS, INCIDENTALOMAS, CORTISOL, PREVALENCE, POLYMORPHISMS
  • Dokuz Eylül University Affiliated: Yes

Abstract

There is growing evidence suggesting a causative relationship between adrenal adenomas and metabolic and cardiovascular deteriorations. Although demonstrated frequently in subjects with subclinical Cushing Syndrome, subjects with non-functioning adrenal adenomas feature a variety of metabolic and cardiovascular consequences. In this review, current data regarding this issue and possible underlying mechanisms have been summarized. (C) 2013 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.