Effect of vitamin E on vascular responses of thoracic aorta in rat experimental arthritis

Cinar M., Can C., Ulker S., Gok S., Coker C., Soykan N., ...More

GENERAL PHARMACOLOGY, vol.31, no.1, pp.149-153, 1998 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 1998
  • Doi Number: 10.1016/s0306-3623(97)00387-x
  • Journal Name: GENERAL PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.149-153
  • Keywords: adjuvant arthritis, vitamin E, vascular endothelium, vascular smooth muscle, CHOLESTEROL-FED RABBITS, ADJUVANT ARTHRITIS, COPPER, CALCIUM, ZINC
  • Dokuz Eylül University Affiliated: Yes

Abstract

1. Vascular contractile and relaxant responses were evaluated in isolated aortic rings of adjuvant induced arthritic rats in comparison with control rats, and the effect of an antioxidant treatment on the development of the arthritis was investigated by vitamin E administration (100 mg/kg/day, IM, for 26 days).