Evaluation of serum xenin and ghrelin levels and their relationship with nonalcoholic fatty liver disease and insulin resistance in obese adolescents

Arslan N., Sayin O., Tokgoz Y.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, cilt.37, sa.11, ss.1091-1097, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 11
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s40618-014-0160-z
  • Dergi Adı: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1091-1097
  • Anahtar Kelimeler: Adolescents, Obesity, Ghrelin, Xenin, Fatty liver disease, IMPAIRED GLUCOSE-TOLERANCE, PEPTIDE XENIN, CHILDREN, SECRETION, HUMANS, LEPTIN, PLASMA, DEGRADATION, HOMEOSTASIS, OVERWEIGHT
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aim Xenin is a peptide of the neurotensin/xenopsin/xenin family secreted from gastric cells and other tissues. The first aim of this study was to investigate the serum xenin and ghrelin levels in obese children and compare the patients with healthy controls. The second aim was to compare the xenin levels in patients with nonalcoholic fatty liver disease (NAFLD) and also with insulin resistance with the patients without these complications.