Investigation of Pd-catalyzed Co(III)-EDTA/hypophosphite inhibition reaction kinetics, mechanism and the evaluation of its analytical application possibilities

Bicer N., Gurkan R., Akcay M., Altunata T.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, vol.69, no.2, pp.123-135, 2004 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.2298/jsc0402123b
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.123-135
  • Keywords: Co(III)-EDTA/hypophosphite, inhibition kinetics, iodide and some amino acid determination, kinetic spectrophotometry and initial rate method, NEUTRON-ACTIVATION ANALYSIS, ION CHROMATOGRAPHY, IODINE, CYSTEINE, CYSTINE, SPECTROMETRY, SPECIATION, MATRICES, IODATE, URINE
  • Dokuz Eylül University Affiliated: Yes


The reaction between Co(III)-EDTA and hyppophosphite ion. catalyzed by Pd(II) was chosen as the indicator reaction. The inhibition kinetics of this catalytic reaction have been investigated by a mechanistic approach in the presence of some inhibitors. Catalysts, other than PdCl2 that is Pt, Au, Ni salts. did not exhibit any effect on the reaction. An original reaction mechanism is proposed based on the experimental data. The important variables were optimized for maximum sensitivity. The calibration graph, which was prepared following the inhibition kinetic method, showed a linear relationship (r = - 0.9878) between the initial rate and iodide in the concentration range of 2-35 ng/cm(3) I- with a detection limit of 1.2 ng/cm(3) I- (3S(b)/m criterion). The RSDs of the method, (N = 5) for 7 and 14 ng/cm(3) weir 1.19 and 0.81 %, respectively. depended on iodide concentration. The method was only applied to the determination of iodide in water, urine, iodized table salt and some drug samples and was compared with the modified Sandell-Kolthoff method.