Simultaneous Single Dexamethasone Implant and Ranibizumab Injection in a Case with Active Serpiginous Choroiditis and Choroidal Neovascular Membrane

Creative Commons License

SAATCİ A. O., AYHAN Z., Durmaz C. E., Takes O.

CASE REPORTS IN OPHTHALMOLOGY, cilt.6, sa.3, ss.408-414, 2015 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1159/000442346
  • Dergi Adı: CASE REPORTS IN OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.408-414
  • Anahtar Kelimeler: Choroidal neovascular membrane, Dexamethasone implant, Ozurdex, Ranibizumab, Serpiginous choroiditis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Intravitreal anti-vascular endothelial growth factor (VEGF) agents seem to be effective in choroidal neovascular membranes (CNV) in association with various entities of posterior uveitis. We herein report a 46-year-old woman who was treated with a simultaneous single intravitreal dexamethasone implant and ranibizumab administration for the treatment of unilateral extrafoveal CNV associated with an active serpiginous choroiditis. Simultaneously with the intravitreal therapy, oral mycophenolic acid (2 x 720 mg) was started, and oral cyclosporine (3 x 100 mg) was then added 2 months later. On the other hand, the fellow eye had been treated for subfoveal CNV but with an inactive disease 4 years previously and ended up with a final visual acuity of counting fingers despite treatment with a single session of photodynamic therapy and 3 subsequent intravitreal ranibizumab injections. Simultaneous administration of anti-VEGF agents and a dexamethasone implant can be a viable approach in eyes with CNV and active serpiginous choroiditis. (C) 2015 The Author(s) Published by S. Karger AG,