Simultaneous Single Dexamethasone Implant and Ranibizumab Injection in a Case with Active Serpiginous Choroiditis and Choroidal Neovascular Membrane

Creative Commons License

SAATCİ A. O., AYHAN Z., Durmaz C. E., Takes O.

CASE REPORTS IN OPHTHALMOLOGY, vol.6, no.3, pp.408-414, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1159/000442346
  • Journal Name: CASE REPORTS IN OPHTHALMOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.408-414
  • Keywords: Choroidal neovascular membrane, Dexamethasone implant, Ozurdex, Ranibizumab, Serpiginous choroiditis
  • Dokuz Eylül University Affiliated: Yes

Abstract

Intravitreal anti-vascular endothelial growth factor (VEGF) agents seem to be effective in choroidal neovascular membranes (CNV) in association with various entities of posterior uveitis. We herein report a 46-year-old woman who was treated with a simultaneous single intravitreal dexamethasone implant and ranibizumab administration for the treatment of unilateral extrafoveal CNV associated with an active serpiginous choroiditis. Simultaneously with the intravitreal therapy, oral mycophenolic acid (2 x 720 mg) was started, and oral cyclosporine (3 x 100 mg) was then added 2 months later. On the other hand, the fellow eye had been treated for subfoveal CNV but with an inactive disease 4 years previously and ended up with a final visual acuity of counting fingers despite treatment with a single session of photodynamic therapy and 3 subsequent intravitreal ranibizumab injections. Simultaneous administration of anti-VEGF agents and a dexamethasone implant can be a viable approach in eyes with CNV and active serpiginous choroiditis. (C) 2015 The Author(s) Published by S. Karger AG,