A case of keratosis follicularis spinulosa decalvans with partial response to acitretin treatment Asitretin tedavisine kismi yanitli bir keratozis follikülaris spinüloza dekalvans olgusu


AKARSU S., İLKNUR T., Canbaz C., LEBE B., FETİL E.

Turkiye Klinikleri Dermatoloji, cilt.21, sa.2, ss.95-99, 2011 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 2
  • Basım Tarihi: 2011
  • Dergi Adı: Turkiye Klinikleri Dermatoloji
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.95-99
  • Anahtar Kelimeler: Acitretin, Darier disease
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Keratosis follicularis spinulosa decalvans (KFSD) is a genetically and clinically heterogeneous dermatosis mainly characterized by extensive keratosis pilaris of the trunk and extremities, follicular inflammation and progressive cicatricial alopecia of te scalp, eyebrows and eyelashes. Less frequent associations are the development of scalp pustules, palmoplantar keratoderma and ocular abnormalities. Although there are conflicting results for efficacy of treatments in KFSD, generally partial, transient or unsuccessful response rates have been reported with various treatment methods including topical emollients and keratolytics, topical and intralesional corticosteroids, systemic antibacterials, oral etretinate, isotretinoin and dapsone. Herein, we report a 21 year-old-male of KFSD who responded partially to acitretin treatment with resolution of the follicular hyperkeratosis and pustules of the scalp. Copyright © 2011 by Türkiye Klinikleri.