Comparison of vitreous and plasma levels of vascular endothelial growth factor, interleukin-6 and hepatocyte growth factor in diabetic and non-diabetic retinal detachment cases.


KOÇAK N., Alacacioglu İ., Kaynak S., Ozcan M. A., Celik O., Yuksel F., ...More

Annals of ophthalmology (Skokie, Ill.), pp.10-4, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2010
  • Journal Name: Annals of ophthalmology (Skokie, Ill.)
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.10-4
  • Dokuz Eylül University Affiliated: Yes

Abstract

We compared the vitreous and plasma levels of proinflammatory cytokines in diabetic patients who underwent pars plana vitrectomy. Levels of proinflammatory cytokines in the vitreous were higher in the diabetic patients than the non-diabetics while the levels of plasma cytokines were similar. It is thought that this increase in the vitreous is effective in the progression of angiogenesis and the development of proliferative diabetic retinopathy.