Alteration of apoptosis-related genes in postmenopausal women with uterine prolapse.

Saatli B., KIZILDAĞ S., ÇAĞLIYAN E., Dogan E., Saygili U.

International urogynecology journal, cilt.25, sa.7, ss.971-7, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00192-014-2347-4
  • Dergi Adı: International urogynecology journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.971-7
  • Anahtar Kelimeler: Apoptosis, Bcl-2 family gene, Pelvic organ prolapse, PELVIC ORGAN PROLAPSE, MUSCLE-CELL APOPTOSIS, VAGINAL APEX, EXPRESSION, PARAMETRIUM, BCL-2, STANDARDIZATION, TERMINOLOGY, COLLAGEN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

We aimed to compare expression levels of antiapoptotic and proapoptotic genes in parametrial and vaginal tissues from postmenopausal women with and without pelvic organ prolapse (POP). We hypothesized that the expression of genes that induce apoptosis may be altered in vaginal and parametrial tissues in postmenopausal women with POP.