Alteration of apoptosis-related genes in postmenopausal women with uterine prolapse.


Saatli B., KIZILDAĞ S., ÇAĞLIYAN E., Dogan E., Saygili U.

International urogynecology journal, vol.25, no.7, pp.971-7, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.1007/s00192-014-2347-4
  • Journal Name: International urogynecology journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.971-7
  • Keywords: Apoptosis, Bcl-2 family gene, Pelvic organ prolapse, PELVIC ORGAN PROLAPSE, MUSCLE-CELL APOPTOSIS, VAGINAL APEX, EXPRESSION, PARAMETRIUM, BCL-2, STANDARDIZATION, TERMINOLOGY, COLLAGEN
  • Dokuz Eylül University Affiliated: Yes

Abstract

We aimed to compare expression levels of antiapoptotic and proapoptotic genes in parametrial and vaginal tissues from postmenopausal women with and without pelvic organ prolapse (POP). We hypothesized that the expression of genes that induce apoptosis may be altered in vaginal and parametrial tissues in postmenopausal women with POP.