Alteration of apoptosis-related genes in postmenopausal women with uterine prolapse.

Saatli, HASAN; KIZILDAĞ, SEFA; ÇAĞLIYAN, ERKAN; Dogan, ÖMER; Saygili, Ugur

doi:10.1007/s00192-014-2347-4

Alteration of apoptosis-related genes in postmenopausal women with uterine prolapse.

Saatli B., KIZILDAĞ S., ÇAĞLIYAN E., Dogan E., Saygili U.

International urogynecology journal, vol.25, no.7, pp.971-7, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 25 Issue: 7
Publication Date: 2014
Doi Number: 10.1007/s00192-014-2347-4
Journal Name: International urogynecology journal
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.971-7
Keywords: Apoptosis, Bcl-2 family gene, Pelvic organ prolapse
Dokuz Eylül University Affiliated: Yes

Abstract

We aimed to compare expression levels of antiapoptotic and proapoptotic genes in parametrial and vaginal tissues from postmenopausal women with and without pelvic organ prolapse (POP). We hypothesized that the expression of genes that induce apoptosis may be altered in vaginal and parametrial tissues in postmenopausal women with POP.