Hyperglycemia is associated with lower levels of urokinase-type plasminogen activator and urokinase-type plasminogen activator receptor in wound fluid

AKINCI B., Terzi C., Sevindik G., Yuksel F., Tunc U. A., Tunali S., ...Daha Fazla

JOURNAL OF DIABETES AND ITS COMPLICATIONS, cilt.28, sa.6, ss.844-849, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jdiacomp.2014.07.013
  • Dergi Adı: JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.844-849
  • Anahtar Kelimeler: Wound healing, Hyperglycemia, Plasminogen activation, Wound fluid, Diabetes, DIABETES IMPAIRS, FIBROBLASTS, MECHANISMS, GENERATION, MORBIDITY, MORTALITY, CELLS, MICE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aims: Wounds in patients with hyperglycemia show impaired healing. Plasminogen activation is crucial in several overlapping phases of wound healing process. In this study, we aimed i) to compare acute wound fluid in patients with hyperglycemia and normoglycemia, ii) to focus on the elements of plasminogen activation in the wound fluid, and iii) to determine if the acute wound fluid characteristics are associated with surgical site infections.