CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.24, sa.6, ss.643-648, 2006 (SCI-Expanded)
Objective Interleukin I (IL-1) family is composed of two agonists, IL-1 alpha and IL-1 beta and IL-1 receptor antagonist, IL-1Ra. The purpose of this study was to determine the relationship between polymorphisms of IL-1 receptor antagonist (IL-1RN), IL-1B promoter and IL-1B exon 5 genes and susceptibility to rheumatoid arthritis (RA) in Turkish population.