Effect of the deposition temperature on corrosion resistance and biocompatibility of the hydroxyapatite coatings


Vladescu A., Braic M., AK AZEM N. F., Titorencu I., Braic V., Pruna V., ...Daha Fazla

APPLIED SURFACE SCIENCE, cilt.354, ss.373-379, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 354
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.apsusc.2015.05.059
  • Dergi Adı: APPLIED SURFACE SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.373-379
  • Anahtar Kelimeler: Bioactive coatings, Magnetron sputtering, Corrosion resistance, In vitro cell viability, CALCIUM-PHOSPHATE COATINGS, IMPLANT MATERIALS, BIOMATERIALS, TITANIUM, ADHESION, BEHAVIOR, FILMS, MODEL
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Hydroxyapatite (HAP) ceramics belong to a class of calcium phosphate-based materials, which have been widely used as coatings on titanium medical implants in order to improve bone fixation and thus to increase the lifetime of the implant. In this study, HAP coatings were deposited from pure HAP targets on Ti6Al4V substrates using the radio-frequency magnetron sputtering technique at substrate temperatures ranging from 400 to 800 degrees C. The surface morphology and the crystallographic structure of the films were investigated by atomic force microscopy (AFM), scanning electron microscopy (SEM) and X-ray diffraction (XRD). The corrosion resistance of the coatings in saliva solution at 37 degrees C was evaluated by potentiodynamic polarization. Additionally, the human osteosarcoma cell line (MG-63) was used to test the biocompatibility of the coatings. The results showed that all of the coatings grown uniformly and that the increasing substrate temperature induced an increase in their crystallinity. Corrosion performance of the coatings was improved with the increase of the substrate temperature from 400 degrees C to 800 degrees C. Furthermore, all the coatings support the attachment and growth of the osteosarcoma cells with regard to the in vitro test findings. (C) 2015 Elsevier B.V. All rights reserved.